🏥 Clinical Data Analysis: Robotic vs. Laparoscopic Hysterectomy¶

Comparative Surgical Outcomes — Panama 2023¶


Author: Edwin Berbey · Senior Data Engineer
Certification: IBM Data Science Professional Certificate
Dataset: Clinical registry of 122 patients who underwent minimally invasive hysterectomy
Tools: Python · Pandas · SciPy · Statsmodels · Plotly

Data provided with institutional authorization. Hospital identities anonymized per standard research ethics practice.


Clinical Background¶

Hysterectomy is the most common major gynecological procedure worldwide. Two minimally invasive techniques have dominated modern surgical practice:

  • Laparoscopic Hysterectomy: Standard technique, widely available in public health systems.
  • Robotic Hysterectomy (Da Vinci System): Robot-assisted technology, available at high-complexity private centers.

This analysis compares the clinical and operative outcomes of both techniques using real-world 2023 data from two Panamanian hospitals — one private (Hospital A) and one public reference center (Hospital B).

Research Question¶

Are there statistically significant differences in surgical time, intraoperative blood loss, and hospital stay between robotic and laparoscopic hysterectomy?


0. Environment Setup¶

✅ Environment ready
   Pandas 3.0.2 | NumPy 2.4.4

1. Data Loading & Cleaning¶

📊 Dataset loaded: 122 rows × 23 columns
   Robotic (Hospital A):      63 patients
   Laparoscopic (Hospital B): 59 patients
   Missing values: 0

2. Descriptive Statistics — Clinical Comparison Table¶

Equivalent to a Table 1 in peer-reviewed medical publications

Table 1 — Baseline characteristics and surgical outcomes by technique
Significance: *** p<0.001 | ** p<0.01 | * p<0.05 | ns = not significant

            Variable Robotic  (n=63) median [IQR] Laparoscopic (n=59) median [IQR] p-value (Mann-Whitney U) Sig.
         Age (years)             48.0 [43.0–52.0]                 45.0 [39.5–49.0]                   0.0185    *
         BMI (kg/m²)             27.0 [25.0–30.5]                 31.0 [27.0–34.5]                   0.0003  ***
         Weight (kg)             70.0 [62.0–80.5]                 76.0 [68.5–88.5]                   0.0221    *
         Height (cm)          159.0 [156.0–164.5]              159.0 [154.0–163.0]                   0.3706   ns
   Uterus weight (g)          161.0 [120.0–256.5]              210.0 [110.0–350.0]                   0.1353   ns
    Uterus size (cm)             12.0 [10.0–13.5]                  12.0 [8.0–14.0]                   0.6312   ns
  Surgery time (min)             76.0 [63.0–94.0]              117.0 [100.5–141.0]                   0.0000  ***
     Blood loss (mL)             30.0 [15.0–50.0]              200.0 [100.0–300.0]                   0.0000  ***
Hospital stay (days)                2.0 [2.0–2.0]                    2.0 [2.0–2.0]                   0.0015   **

3. Exploratory Data Analysis¶


4. Hypothesis Testing — Statistical Inference¶

The Mann-Whitney U test (non-parametric) was selected because:

  • Normality cannot be assumed with n < 200 per group
  • Surgery time and blood loss exhibit positive skewness
  • It is the standard test in clinical comparative studies of this type

H₀: No significant difference between the medians of both techniques
H₁: A significant difference exists (α = 0.05, two-tailed)

Variable                       Robotic median   Laparosc. median   U statistic    p-value             Result
------------------------------------------------------------------------------------------------------------
Surgery Time (min)                       76.0              117.0           646     0.0000      SIGNIFICANT ✅
Blood Loss (mL)                          30.0              200.0           164     0.0000      SIGNIFICANT ✅
Hospital Stay (days)                      2.0                2.0          1516     0.0015      SIGNIFICANT ✅
Uterus Weight (g)                       161.0              210.0          1566     0.1353    Not significant
BMI (kg/m²)                              27.0               31.0          1150     0.0003      SIGNIFICANT ✅
Age (years)                              48.0               45.0          2318     0.0185      SIGNIFICANT ✅

Significance level α = 0.05 | Test: Mann-Whitney U (two-tailed)

5. Correlation Analysis¶


6. Regression Analysis — Predictors of Surgical Outcomes¶

=================================================================
MODEL 1 — OLS Regression: Predictors of Surgery Time (min)
=================================================================
                   Coef.  Std.Err.       t   P>|t|   [0.025    0.975]
Intercept        83.1214   24.0136  3.4614  0.0008  35.5595  130.6834
bmi               0.5862    0.4042  1.4503  0.1497  -0.2144    1.3867
uterus_weight_g   0.0845    0.0141  5.9931  0.0000   0.0566    0.1125
uterus_size_cm    0.3061    1.1955  0.2561  0.7983  -2.0617    2.6739
age              -0.2291    0.3318 -0.6907  0.4911  -0.8862    0.4280
technique_bin   -27.2412    5.5359 -4.9208  0.0000 -38.2056  -16.2767

R²  = 0.6229
Adj. R² = 0.6067
F-statistic p-value = 0.000000
=================================================================
MODEL 2 — OLS Regression: Predictors of Blood Loss (mL)
=================================================================
                    Coef.  Std.Err.       t   P>|t|    [0.025    0.975]
Intercept          3.7960   76.3974  0.0497  0.9605 -147.5187  155.1108
bmi                2.2444    1.2859  1.7454  0.0836   -0.3025    4.7913
uterus_weight_g    0.0559    0.0449  1.2457  0.2154   -0.0330    0.1448
uterus_size_cm     4.4989    3.8033  1.1829  0.2393   -3.0341   12.0319
age                1.2454    1.0555  1.1800  0.2404   -0.8451    3.3359
technique_bin   -160.1828   17.6119 -9.0951  0.0000 -195.0655 -125.3001

R²  = 0.5369
Adj. R² = 0.5169
F-statistic p-value = 0.000000

7. Summary Dashboard¶


8. Conclusions¶

Key Findings¶

Outcome Robotic (median) Laparoscopic (median) p-value Interpretation
Surgery time 76 min 117 min <0.001 Robotic significantly faster (−35%)
Blood loss 30 mL 200 mL <0.001 Robotic ~6.7× less blood loss
Hospital stay 2 days 2 days 0.002 Distribution differs despite equal median
BMI 27 kg/m² 31 kg/m² <0.001 Different patient profiles by center
Uterus weight 161 g 210 g ns No significant difference

Interpretation¶

  1. Robotic technique shows significant intraoperative advantages in surgical time (−35%) and blood loss (−85%) compared to laparoscopic, with high statistical evidence (p<0.001).

  2. Hospital stay did not differ meaningfully (median 2 days in both groups), suggesting that intraoperative benefits do not translate into shorter postoperative recovery at this sample size.

  3. Laparoscopic patients presented higher BMI (median 31 vs. 27 kg/m²), likely reflecting referral differences between public and private centers rather than a technique effect.

  4. Surgical technique is the dominant predictor of both surgery time (R²=0.62) and blood loss (R²=0.54) in the regression models, outperforming uterus weight, BMI, and age.

Limitations¶

  • Retrospective observational design: causal inference is not possible
  • Patients come from two centers with different profiles (private vs. public)
  • Near-zero complication rate limits inferential analysis of that variable
  • n=122 is adequate for descriptive and basic inferential statistics, but insufficient for meaningful subgroup analysis

Edwin Berbey (Timmy) · Senior Data Engineer
IBM Data Science Professional Certificate
🌐 Portfolio · LinkedIn

Data provided with institutional authorization. Hospital identities anonymized per standard research ethics practice.